Presented Abstracts
"Confronting Biological Threats:
Biosecurity, Biological Weapons Nonproliferation, and Regional Cooperative Mechanisms”
Amman, Jordan
October 27 - 29, 2008

Planning and capacity building of human and animal health systems-
 the example of avian influenza

William K. Ampofo1
In cooperation with Lawson Ahadzie2, M. Agyen Frempong3, E.B.M. Koney3, Gaari-Kwaku3, E. Barnor3, Ernest Lamptey4, Richard Suu-ire4, Gregory Raczniak5, Richard Killian6, Fulgence Sangber-Dery6, Michael Adjabeng2, Kofi Bonney1, Michael Wilson1, Diana Boakye7, Joseph Ankrah7, Harry Opata8, Alexander Nyarko1 and George Amofah2.
1Noguchi Memorial Institute for Medical Research, 2Ghana Health Service,3Veterinary Services Directorate, 4Game and Wildlife Division, 5US Naval Medical Research Unit-3, 6Quality Health Partners/Engender Health, 7National Disaster Management Organization and 8World Health Organization.

Introduction:
Since 2003, highly pathogenic Avian Influenza (AI) has spread to Asia, Europe and Africa and is a major health threat for domestic poultry and humans. In Africa, weak infrastructures and institutional capacities are major limitations for appropriate prevention and response strategies. In 2005 in Ghana, the Ministries of Health, Agriculture, Forestry/Lands/ Minerals and Interior, together with international development partners, created the Avian Influenza Working Group. This body has coordinated the development of Ghana’s plans and actions to address the risk of an AI pandemic.

Methodology:
A rapid review of key systems for disease surveillance and control in animals, humans and disaster preparedness was conducted at national, regional, and district levels. This led to national (and regional) AI preparedness and response plans based mainly on internationally recognized phases of pandemic influenza with trigger activities for initiation of further responses. Following the 2007 bird flu outbreak in poultry in Ghana, updating of the national framework is underway with various activities in the animal/ human health sectors plus public private partnerships.

Results:
Lessons learned include the recognition that multi-sectoral approaches can be effective, improved capacity of human/animal health systems to detect and manage AI infections, nationwide awareness/education on biosecurity and the conduct of simulation exercises to heighten preparedness.

Conclusion:
There is a pressing need to improve the capacity of human/animal health facilities to better manage highly infectious pathogens across Africa. The AI pandemic threat illustrates the requirement for local anticipation, coordination and continuous preparation towards dire global health issues.

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Biosecurity in Jordan - Medical and Industrial Waste Treatment Plant
for Greater Amman and Middle Governorates
Mr. Luciano Borin
President, Action Stream International - Italy


The Government of the Hashemite Kingdom of Jordan (GoJ) wishes to outsource to a private investor the design, financing , construction, operation and maintenance of a Medical and Industrial Waste Treatment Plant (the Plant) under a Public-Private Partnership scheme (the Project) structured on the basis of a Build-Own-Operate and Transfer (BOOT) contract between the GoJ and a special purpose company (SPC) to be formed by the private investor under the Laws of Jordan.

With the exception of a small unit established in the north of the country , Jordan does not have centralized facilities to treat medical and industrial wastes. A few hospitals operate treatment units which are not fitted to meet the environmental standards required by Jordan law in terms of gaseous emissions and disposal of liquid effluents and solid residues. Industrial wastes are handled through ad-hoc arrangements which are difficult to monitor and are often non-compliant with environmental regulations.

The resulting risks of health hazards for the population deriving from the above situation are substantial and have prompted the GoJ to promote, in line with international experience, private investment for the establishment of a modern centralized treatment facility which will handle both medical and industrial wastes. It is envisaged that medical wastes will be sourced from the Greater Amman Municipality (GAM) and Middle Governorates, while industrial wastes will be sourced from the GAM only. The Project includes not only the treatment of the wastes, but also their collection, transport to the Plant site at Ghabawi and transport and disposal of treatment residues from Ghabawi to the special wastes landfill at Swaqa.

The foreseen plant will include:

1 – A medical and industrial waste incineration plant of approximately 18,000 tons/year capacity and an
     ancillary pre-treatment facility for oily waste of 5,000 tons/year capacity, at Ghabawi ( 23 km from central
     Amman);

2 – A physico-chemical treatment plant of 2,000 tons/year capacity at Ghabawi;

3 – A solidification plant for waste and residues, with a capacity of approximately 4,400 tons/year at
     Ghabawi; and

4 – A Class I landfill for slag and residues with a capacity of approximately 17,000 tons/year at Swaqa (150
     km from Amman).

This document illustrates the Project key features and outlines some lessons learnt during the negotiation process that can be applicable to future BOOT initiatives in similar and other fields.

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Best Practices for Laboratory Standards in Biosafety, Biosecurity and Collaboration on Technology Development
Dr. Robert Bull
FBI Laboratory - US


The development of laboratory best practices are critical to the acceptance of biological safety and security policies. Key to any plans for biological security is an accepted set of standards for biological safety. Biological safety standards have been developed through the input from experts in the laboratory and are intended to protect those that work in the laboratory, as well as the broader community. Biological safety practices rely on a consensus of levels that define the practices as appropriate to work with biological materials. This is similar to the approach that is taken for biological security. Using a parallel approach to biological safety, biological security of laboratories working with biological materials have implemented practices to meet the legal and administrative requirements necessary, as defined by governmental oversight. Insuring input from those that execute biological security policies is intended to maximize the public benefit. Any plan for biological security should define the location the work is performed, the engineering requirement necessary to control the material in the facility, and the personnel working with the biological material. Defining where the work is performed allows for oversight of the facilities, insuring that work is performed safely and with appropriate resources for securing biological materials. Knowing who is working with the biological materials ensures that training and appropriate background considerations conform to the standards that have been set.

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Role for Export Controls in Biosecurity and Non-Proliferation
Dr David M. Coates
Cooperative Threat Reduction at the Defence Science and Technology Laboratory - UK
 

Much money and effort is currently being put into improving biosecurity of laboratories working with dangerous pathogens and toxins. However, biosecurity does not stop at the perimeter fence of such laboratories, which are often asked to supply micro-organisms and other dual-use materials to other countries as part of the legitimate and important fight against disease. Effective export controls need to be in place to prevent the inadvertent transfer of dangerous pathogens and toxins into the hands of those who might want them for offensive BW purposes, or allow them to be diverted for such use. Such controls help states fulfil their obligations under the BTWC, but to be effective they need to be internationally consistent and relevant, competently and expertly assessed and implemented, and understood by both exporters and officials.

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How to Face Bioterrorism: The Role of Clinical Microbiology
Maria Rita Gismondo
Clinical Microbiology Unit, BSL4 Lab, L. Sacco University Hospital of Milan, Italy
 

The CDC and other health institutions in Europe have established a Bioterrorism Preparedness and Response Program that addresses public health response to bioterrorist actions. These public plans include disease surveillance, laboratory diagnosis of biological agents, epidemiologic investigation, communication (between local, state, and federal public health authorities), preparedness planning, and readiness assessment.

The skill of the Lab of Microbiology is the cornerstone of the plans. In fact, its role is the health surveillance, by detection practice, the rapid diagnosis, the epidemiologic investigation and it contributes to the implementation of control measures. According to the biosafety level, the lab can face different pathogens and it contributes to the public plan.

The first line labs (Level A) with II level cabines rules-out and forward organisms; Level B and C Labs with BSL-2 facility + BSL-3 Safety Practices have a role of Limited confirmation and Transport; Level D Lab BSL-4 is the Highest level characterization (Federal). The labs network is visualized as a pyramidal structure.

In Europe the organization is at national level end each country defines the own plan of intervention.

The Author shows the Class A microrganisms and their possibility of detection, the epidemiological network and new diagnostic approach to bioterrorism emergency.

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Biotechnology Research: Biorisks and Biosecurity Responses
Elisa D. Harris
Senior Research Scholar, Center for International and Security Studies at Maryland - US


Bioterrorism is a major concern of many Western policymakers, but a source of danger involving modern biology has been largely overlooked: the possibility that legitimate biotechnology research in academic, government, or industry laboratories could result, either deliberately or inadvertently, in destructive consequences. Research with potentially destructive applications is being carried out in laboratories around the world. Well known examples of such dual-use research include the mousepox experiment in Australia and the poliovirus experiment in the United States. This presentation will explore both the nature of the dual-use problem in microbial biotechnology research and potential measures to mitigate the threat.

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Handling CBRN Incidents in the Netherlands
Dr. Sally Hoffer
Dutch National Institute for Public Health and the Environment (RIVM),
Advisory Service for the Inspectorate, Environment and Health – Netherlands
 

Due to the decentralised emergency response model in the Netherlands the local and regional authorities lack the possibility to acquire and maintain expertise and facilities necessary to cope with none-routine incidents like small-scale CBRN incidents. In these incidents RIVM and the Dutch National Laboratory Network play a key role in generating, collecting, integrating and scientific interpretation of data and converting these data into information that is directly usable by authorities in charge. When for example a pathogen has been released, the Netherlands have several systems in place to respond effectively

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Dual-use Research, Bioweapons and Biosecurity
Dr. Iris Hunger
Head of Research Group for Biological Arms Control
Carl Friedrich von Weizscker Centre for Science and Peace Research
University of Hamburg - Germany
 

Because of the strong dual use character of the life sciences, biosecurity measures always apply to legitimate activities, even if intended to prevent illegitimate ones. The extent of the modern life sciences makes it impossible to control all dual use activities. Biosecurity measures have to focus on activities with a particularly high misuse potential. There is no agreement so far what such particularly dangerous activities are. One approach uses the types of agents involved in classifying activities as particularly dangerous. Another approach considers activities to be of
particular concern if certain results are expected or accidentally achieved.

It is to be expected that activities of concern are frequently carried out in maximum containment facilities and in biodefence programmes. Both, therefore, need to receive particular attention when designing biosecurity measures.

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Regional Cooperation Mechanism for Enhancing Biosafety and Biosecurity
Ali Karami, Ph.D
Research Center of Molecular Biology, Institute of Military Medicine
Baqiyatallah University of Medical Sciences - Iran
 

Rapid advances in Molecular Biology, Biotechnology, Recombinant DNA Technology, Genetic Engineering, Omics (Genomics, Proteomics, transcriptomics and metabolomics), Nanobiotchnology, Synthetic Biology, System biology and other emerging, Converging and disruptive science and technologies over the past decade have brought enormous benefits to medicine, public health, food industry and agriculture but have created concerns to reduce ant threat to humanity.

Differentiating between Biosafety and Biosecurity
As simple definition, Biosafety protects people from germs and biosecurity protects germs from people.

The main question is how we can protect our society, region and the world from misuses, abuse, dual use or misconduct in research, development and applications of these new technologies.

Several points and steps are critical to expand the culture of the issue to implement the Safety and security across the nations, region and the world:
1- Clear definitions and understanding of the terms and implications.
2- Differences in the national scientific and technological capacity in planning, regulation and national
    legislations.
3- We can not implement and enforce single international biosafety and Biosecurity regulation for all countries.
    Biosafety and biosecurity procedures and practices vary enormously from country to country according to
    level of technological development therefore "one size fits all" approach should be avoided in dealing with
    the issues.
4- Steps should be taken to first educate, build the capacity, enhabce the culture, knowledge, basic
    requirements and personnel…. To implement the regulations.
5- The Universities, research institutes, laboratories and scientists should be encouraged to convene
    seminars, workshops and prepare research papers to raise the awareness. Training programs and materials
    on biosafety and biosecurity regulations and biomedical ethics should also be improved and inserted in
    university curricula.
6- Scientific community and industry that play a significant role in the development and application of
    biotechnology should be involved in devising educational programs.
7- Biosafety and biosecurity measures and regulations should avoid any restrictions on exchange of scientific
    discoveries in the field of biology for research, development, prevention, diagnosis and treatment or
    disease and other peaceful purposes.
8- The promotion of international scientific and technological cooperation and exchange of information
    according to article X of the BWC regarding results of scientific research constitutes yet another effective
    assurance for the use of bio sciences to remain peaceful.
9- Finally all of these regulations should not leave individuals and scientists with the impression that these
    standards are not designed against them or their scientific activities.

Regional and international actions
We need to expand our activities in the following areas

1- Close collaboration of scientists of the region for exchange of ideas, information sharing exchange of
    science, technology and transparency.
2- Establishing networks among researchers.
3- Active participation of scientific societies (NGOs)
4- Regional meetings, Seminars and workshops to discuss the national capacities, weaknesses and
    experiences for national legislations.
5- In order to improve implementation measures, it is encouraged to strengthen coordination with relevant
    international organizations, such as the WHO, FAO, OIE to engage in mutual feedback on the discussions
    concerning biosafety and biosecurity.

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Bioterrorism Threat
Barry Kellman
International Weapons Control Center
DePaul University College of Law – US


What’s the gravest security threat facing humanity? A nuclear explosion would be horrible, but terrorists would be hard pressed to get nuclear bomb. They certainly could not make one. No one should discount this threat, but neither should we be blinded to more realistic dangers – the dangers of bioterrorism. Terrorists have announced their desire to attack us with a biological weapon which is much easier to make than a nuclear bomb. Germs can be carried undetected through any airport in a small shampoo or perfume bottle. A contagious disease would spread misery without regard for boundaries, race, religion, or nationality.

Altogether, techniques that were on the frontiers of science only a decade or two ago are rapidly mutating as progress in the biological sciences enables new ways to produce lethal catastrophe. Every passing day it becomes slightly easier to commit a violent catastrophe than it was the day before. For terrorists who seek to rattle the pillars of modern civilization and perhaps cause it to collapse, effective use of disease would set in motion political, economic, and health consequences so severe as challenge government’s ability to maintain our security. In an attack’s wake, no one would know when it is over, and no official could credibly tell us where and when we might be safe. To stop modern civilization in its tracks, bioterrorism is the way to go.

We must appreciate the global nature of the problem. Perpetrators from anywhere can get disease agents from virtually everywhere. The knowledge needed to weaponize pathogens is available on the Internet. An attack can be prepared through easy networks of transnational communication. Public health responses would have to be internationally coordinated. New modes of international legal cooperation would be needed to investigate the crime. Indeed, the threat of bioterrorism shrinks our world into an interdependent neighborhood.

Yet, bioterrorism dangers are unnecessarily high because national and international anti-bioviolence strategies are gap-ridden, often incoherent and not globally observed. As a result, we are all virtually naked in the face of unacceptable dangers. No other threat presents such a stark contrast between severity of harm and a failure of leadership to reduce risks.

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Biodefense in the Middle East
Steve Kornguth
Center for Strategic and Innovative Technology
and
Director, Biological and Chemical Defense, the Institute for Advanced Technology, the University of Texas at Austin - US

Emergent and/or intentionally caused highly infectious diseases are low probability events that have profound and highly disruptive consequences on economies and the political and medical infrastructure of a nation or region. Ensuring the safety of the populace against a biological attack relies heavily upon the ability to predict, prevent or mitigate clinical symptoms of disease. Capabilities for predicting and negating emergent disease or biological attack include: 1) monitoring changes in the wellness of humans and livestock; 2) robust sensor systems, with very low false positive/negative events, that can detect abnormal levels of pathogen or host markers of infection. Effective communication of emergent threat to central and local governments can enable these authorities to formulate a plan of action and initiate countermeasures that may mitigate the threat. Mitigation involves preparedness of responders and sustaining the capability of responders to maintain high levels of performance during potentially long-lasting operational activities.

Fused data from multiplexed sensors responsive to a wide range of pathogens and host markers would provide the excellent capabilities for early alert of threat from biological agents. Such data would decrease the risk of false positive/negative alerts that can result in an inoperable system. Genomic databases for humans and pathogens will provide much-needed information on the susceptibility/resilience of the host population to the agent and the vulnerability of the pathogenic virus and/or bacteria to vaccines, antibiotics or antivirals. The increase globally, in the number and capabilities of biotechnology firms and research units, enables the rapid identification of emergent biothreat agents in local nation/states and the rapid pinpointing and strain identification of intentionally released pathogen into the populace or the unintentional compromise of pathogen containment. Tracking and detailing the production of vaccines on a global scale will enable rapid resource allocation in the case of disease outbreak. Certain geographical regions and human populations (i.e. particularly mobile individuals or people with genetic susceptibility to disease or who are immuno-compromised) may serve as vectors for transmission of disease, and the geographical location of these areas and habitations can be used to calculate risk factors. Local wildlife can, in turn, provide a reservoir of pathogenic infection that provides long-term sanctuary for disease. An integrated pathogen detection and identification system coupled with an alerting system can reduce the impact of emergent disease or intentional threat. Such regions and hosts should be more closely monitored for prediction and detection of an event.

This Conference also has a focus on threats from chemical agents and from toxic industrial chemicals. The ability of chemical toxicants to modulate the immune response of hosts to infectious agents creates a nexus of interest for joint efforts in biological and chemical threat management.

International cooperative efforts in the detection of and response to biological and/or chemical agents could potentially increase early detection capabilities and produce additional resources including stockpiled pharmaceuticals and trained responders who can relieve limited resources in the area of attack. Securing such cooperation, particularly biological, chemical and radiation defense communities of the Middle East, is a priority in preparing a response for endemic disease outbreak or intentional attack. The first step towards establishing a multi-national response is to establish and maintain a team of trusted investigators amongst the proposed partner states. This trust can be built by providing information to industry and biomedical researchers; the researchers could archive pathogen samples and document vaccine production in the partnering states. A multinational response team could provide the international credibility needed regarding release of an alert of emergent disease. The natural resources and human capital of each country can best be put to use in a combined defensive strategy: for example, the highly trained medical professional force of one nation could be dispersed to threat locations in a neighboring state while the biotechnology resources of a developed nation can be contracted to produce therapeutic aid. Establishing trust in the present will ensure that such byways remain open to rapid cooperative responses in threat situations. The opportunity provided by this conference in Jordan is of great relevance because Jordan plays a unique role as a hub of communications for Middle East nations and maintains relations with all surrounding states. Jordan and Arab Institute for Security Studies (ACSIS) can initiate a leading role in the coordination of health emergency response networks for the benefit of the entire Middle Eastern region.

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Asian view on National and Regional Legislation Implementation
Ajey Lele
Institute for Defense Studies and Analyses (IDSA) – India


Post, Sixth Review Conference of the Biological Weapons Convention (BWC) one of the major areas of discussions have been the importance of National and Regional Legislation Implementation to avoid proliferation of Biological Weapons/technology. The major focus of the UN meetings like the Meeting of Experts (MX-Aug 2007) have revolved around identifying and discussing ways and means to enhance national implementation, including enforcement of national legislation, strengthening of national institutions and coordination among national law enforcement institutions. From the Hague protocol of 1907 to, the 2004 UN Security Council Resolution 1540 the UN has always asked the state parties (in some form or other) to take and enforce effective measures against the proliferation of WMD, their means of delivery and related materials.

At the backdrop of above this paper attempts to provide an Asian view on the National and Regional Legislation Implementation. The paper highlights the measures taken by few important Asian states in this arena giving due cognizance to their political, social and scientific (technological) compulsions.

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Regional Engagement to Enhance Biosecurity:
Lessons from the Australia / Indonesia co-hosted BWC Regional Workshops
Robert Mathews
Head, NBC Arms Control in the Human Protection and Performance Division of the Australian Defense Science and Technology Organization (DSTO) – Australia

This presentation will commence with a discussion of the rationale and objectives of the Biological Weapons Convention (Biosecurity) Regional Workshops co-hosted by Australia and Indonesia in the South East Asia / Pacific, will then discuss of some of the major outcomes flowing from these workshops, and will conclude with lessons that may be applicable in the development of regional co-operation for the enhancement of biosecurity in other regions.

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Outreach, Awareness-raising and Codes of Conduct
Robert Mathews
Head, NBC Arms Control in the Human Protection and Performance Division of the Australian Defense Science and Technology Organization (DSTO) – Australia

This presentation will commence with a discussion of the importance of outreach and awareness-raising among the various biological science and biotechnology communities, based on the obligations under the Biological Weapons Convention and the dual-use dilemma in biological sciences, and will then discuss the role of various Codes of Conduct (including Scientific Society Codes and Workplace Codes) in enhancing biosecurity, and raising the barriers to BW-proliferation and bioterrorism.

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Disaster Risk Reduction, Global and National Frameworks and Mechanisms
Mostafa Mohaghegh
Head of UNISDR Regional Office for West Asia and North Africa, Cairo


The statistics show a growing trend of disasters triggered by natural hazards in the recent decades. The disasters continue to impose huge possess on communities and nations and hamper the socio-economic development capacities and programs in particular in the developing countries. The vulnerability caused by the imbalanced development and environmental degradation contributes to natural hazards become destructive disasters and leave larger negative impact on communities.

The Hyogo Framework for Action (HFA) adopted by the World Conference on Disaster Reduction in Kobe, Japan in 2005 and endorsed by the United Nations General Assembly in the same year, presents a series of global Strategic Goals and Priorities for Action for the period of 2005 to 2015. The HFA promotes recognition of disaster risk reduction as top development priority at national, regional and international levels and provides a number of actions to be taken by all stakeholders in various areas such as risk understanding and assessment, institutional capacity development, communication and early warning and complementarity between risk reduction and disaster preparedness and response. The HFA also provides a number of measures at national level such as inclusion of the disaster risk reduction at highest national development planning and establishment of National Platform for Disaster Risk Reduction.

The main objectives of the mentioned frameworks and mechanisms are to give the due recognition of the importance of disaster risk reduction and prevention as top priority and to ensure a multi-stakeholder and coordinated approach in reducing disaster risks. Considering the increasing challenges the nations and communities are facing such as climate change and environmental degradation, unplanned urban growth and poverty, developing more effective response measures such as reducing vulnerabilities and increasing the resilience of people and communities seem to be a better solution in long term.

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An Overview on Biological Weapons Threat
Natividad Carpintero-Santamaría and Guillermo Velarde
Institute of Nuclear Fusion – Polytechnic University of Madrid - Spain

Presently, conventional biological agents and conventional biological research has turned into a interdisciplinary science: biotechnology or biological engineering whose legitimate use, if maliciously intended, would enlarge the scope of the traditional threat posed by conventional bacteriological agents.

Related to biological threat, we can underline the absence of biological attacks to people in the worst years of terrorism during the Cold War. However there are several reports on different incidents in which agriculture and food have been main targets, being this last aspect another important factor to be considered. To this respect, biotechnology industry with the provision of materials (bioreactors) and new methods of research in cellular biology, microbiology, biochemistry, etc represent another challenge in the non-proliferation of biological weapons.

The BWC (1972) with the prohibition of development, production and stockpiling of biological and toxin weapons has proven to be insufficient to stop its proliferation. Firstly, because several countries have not joined it, and secondly, due to the absence of a protocol that allows the verification of the compliance of the terms by the State Members.

Many of us wonder if it is possible to prevent a covert biological attack. This paper analyzes the present situation of potential biological threat with a special emphasis in the efforts carried out by governments, institutions and the scientific community in order to establishing a program bound to minimize any biotechnology mismanagement or misuse, which could lead to both a qualitative and quantitative strategic damage.

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Developing Biosafety and Biosecurity measures: A case of Uganda
Maxwell Otim Onapa
Deputy Executive Secretary of Uganda National Council for Science
and Technology (UNCST) - Uganda

Globalization has collapsed distance and made the world economically, socially, politically, culturally and scientifically integrated.

New challenges are appearing, these range from bioterrorism to transboundary spread of epidemic diseases; rapid spread of harmful germs and diseases.

The global PH systems in particular under strict scrutiny since animal diseases have rocked global PH, security, trade and economies

There is an elevated risk that biological agents could be used for bioterrorism and as weapons of mass destruction in the future (Fear of military use limited).

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The Emerging Biological Weapons Threat And Proliferation
Sudha Raman
Research Coordinator - The United Service Institution of India (USI)
Centre for Strategic Studies and Simulation (USI-CS3) - India

The Problem
Of the triad of weapons of mass destruction, essentially it is the nuclear weapons that have remained at the centre of world focus and to some extent the chemical weapons. The fight against possession and production of biological weapons (BW), which could in fact be categorised as a silent threat, with a fatality rate probably greater than nuclear weapons, has at best remained muted. Ironically, in spite of the Biological and Toxin Weapons Convention (BTWC) of 1975, not to forget the Geneva Protocol of 1925 and the Australia Group, number of states continue with their research and development in biological weapons.
The contextual relevance of biological weapons threat arises out of its possible possession by non-state actors i.e., the terrorist groups, independent or supported by state actors. Here the attempts by the Taliban and the Al-Queda to expand modes of terrorism through the medium of use of biological weapons need to be considered. Biological weapons proliferation thus is serious in that it is increasing the probability of serious bioterrorism incidents. This altered international security environment compels us to work towards broader nonproliferation activities and stem and resolve the grave risks posed by bio-terrorism and outbreaks of infectious diseases.

The Scene

The use of anthrax threat in the US was no minor accident. The presence of large, well-resourced and in some cases state-supported organizations that train and programme the non state actors is extremely worrisome. Equally worrisome is the presence of organizations that would use biological weapons to further certain goals. Such organizations could use biological pathogens that are easily available.
It is when surveying the security measures that one needs to take into account a few vital facets of BW like the dual-use nature of biological materials and equipment, the trivial amounts needed to cause an outbreak of diseases, and the relative ease with which these can be produced or procured. Biological agents are easier and cheaper to produce than either nuclear materials or CW agents, and the necessary technology and know-how is widely available. Any nation with even a modest pharmaceutical industry is capable of producing BW agents.
These are weapons that act as a poor but effective counter to the offensive posture of a more technologically sophisticated adversary.
Many countries believed to possess such weapons or to be developing them will not admit to having such a programme. Even past offensive programmes lie buried. There is barely enough info on the doctrines (if any), intent and decisions on use of BW stored in a country’s arsenal.

India and BW
India has ratified the Biological and Toxin Weapons Convention (BWC) on 15 July 1974 and has pledged a commitment to abide by it. India itself is in the throes of threats from non-state actors and has to find means to fight the menace. A joint effort to fight and restrain possession and use of BW is in the interests of all. It is in this background that my paper would design its answers to the following questions from an Indian perspective:-

(a) How many nations seek to acquire different types of BW and for what?
(b) Can proliferation of BW/agents be controlled at the source?
(b) In the light of the threats from non state actors, how can efforts for nonproliferation be leveraged? How
     does one go about with an internationally-constructed, effective bio-threat nonproliferation system?
(d) What is the course to be adopted to successfully stem dangers of use of BW by state and non state
     actors?
My paper will answer these queries from the Indian point of view and wherein lies the concern of India regarding these weapons, how much efforts will be put by my country towards a world free of such weapons by strengthening, especially while framing its foreign policy, its relations with countries that may not be very open with its BW programme.

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National Implementing Measures for Effective Biosafety and Biosecurity — VERTIC’s National Implementing Measures (NIM) Project
Scott Spence
Chemical and Biological Weapons Legal Officer at the (VERTIC) - UK

The presentation provides an introduction about VERTIC objectives and functions. Additionally, the following themes will be addressed:
• what national measures States should adopt to prevent and prohibit the proliferation of biological weapons
• how States can accomplish the effective implementation of national measures,including biosecurity measures
• the benefits of comprehensive national implementing measures

On “what”, the presentation will discuss:
• National measures (primary legislation, regulations) to regulate and monitor activities involving controlled
  agents and toxins
• Additional measures to ensure full implementation of the Biological and Toxin Weapons Convention and
   related provisions of UNSCR 1540

On “how”, the presentation will discuss VERTIC’s National Implementing Measures Project, which covers:
• Comprehensive analysis of States’ existing legislation
• Direct, cost-free legislative drafting assistance in capitals
• VERTIC’s legislative drafting tools and fact sheets

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Public-Private Partnerships for Global BioSecurity
Mr. John Stammreich1, Dr. Thomas Austin2 and Dr. Charles David3
1Vice-President Global Strategy, Boeing Company.
2Director, CBRNE Programs, Boeing Company.
3Senior Scientist Biosecurity, Boeing Company.

The world faces signficant biological security challenges. There currently is no effective and affordable global strategy in place. Existing plans, capabilities, research and development are costly and limited in coordination and effectiveness. Proposed biosecurity solutions must balance effectiveness, affordability, and public confidence. In order to build more effective global biosecurity, governments must enlist the resources of the private sector. The establishment of a "Global BioSecurity Public-Private Partnership (P3)" involving the public sector, private sector, academia and non-governmental organizations is an important first step for improved global biosecurity. The P3 will serve to create a consensus among the stakeholders in addressing biosecurity countermeasures priorities. The P3 will serve to share requisite information and data to evaluate alternative countermeasures using risk management based analytical methodologies to support informed dialogue and decision making.

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Responding to Intentional Biological Threats in Agriculture – Agroterrorism, Post-harvest Food Bioterrorism and Emergency Preparedness
Raymond A. Zilinskas, Ph.D.
Center for Nonproliferation Studies (CNS), Monterey Institute of International Studies, US

The food supply systems of most countries are comprised of two phases – the pre-harvest and post-harvest phases. Each is vulnerable to sabotage by criminals or terrorists, although the second is the more likely to be so targeted since it is easier to breach and affect. This is so because many or most food processing, packing, and distribution facilities neglect to check on the background of the persons they employ and lack adequate physical security to prevent outsiders from accessing the food and beverage products processed and packaged by these facilities.

This presentation will identify the vulnerabilities of each phase to sabotage by using a threat assessment schema developed by Bruce Hope of the Oregon State Department of Environmental Quality. Experience from a table-top exercise conducted in Salinas, California, that modeled a deliberate sabotage of fresh spinach with Shigella dysenteriae will be used to illustrate aspects of the presentation. The presentation will end with a discussion of measures that have been taken at the federal level to safeguard the U.S. food supply system and that may have lessons for other countries.